Montreal biotech Telesta Therapeutics is cutting 15% of its payroll to conserve cash as the company works to get its once-rejected cancer drug back on track.
Most of the layoffs will affect Telesta’s manufacturing operation, management said, and the company is simultaneously slashing its expenditures. The biotech reported cash and equivalents totaling $20.3 million at the end of 2015.
Telesta, which trades on the Toronto exchange, is trying to pick up the pieces after the FDA rejected its application to win approval in bladder cancer last month. The company’s drug, MCNA, failed to satisfy regulators’ demands, and the FDA asked Telesta to conduct at least one more Phase III trial to establish the treatment’s efficacy and safety.
Now Telesta is requesting a so-called Type A meeting with the FDA, angling to sit down with agency staff to “obtain clarity” on what it needs to do to win approval, the company said in a statement.
“In parallel, we are working with our board of directors to review of all of our strategic options over the next few months,” CEO Michael Berendt said in a statement. “We are very aware that this review must be conducted and completed in a timely fashion to ensure that we conserve our key cash resources.”
Since MCNA’s rejection in early February, Telesta has been hinting that it may try to sell itself, with Berendt saying at the time that “the current climate of uncertainty in the financial markets has created opportunities for well-capitalized companies that were simply not available even a few months ago.”
Last year, Telesta flipped the European rights to MCNA to Ipsen, banking a $10 million upfront payment with a shot at $127 million more if the drug wins approval overseas.
By Damian Garde
Source: Fierce Biotech
Giovanni Caforio, the former CEO of Bristol Myers Squibb, is set to become the next board chairman of Novartis, which on Tuesday proposed the pharmaceutical industry veteran as its pick to replace Joerg Reinhardt in the role next year. Reinhardt has served as Novartis’ chair since 2013 and plans to retire when his 12-year term ends in 2025.
GE HealthCare has raised the curtain on two ultrasound systems equipped with artificial intelligence programs designed to assist in diagnosing conditions in women’s health, including obstetric exams. The Voluson Signature 20 and 18 imaging systems include AI tools capable of automatically identifying and annotating measurements of fetal anatomy.
Scientists from the University of Edinburgh’s School of Chemistry have revealed a new sustainable method of manufacturing complex molecules that could reduce waste produced during drug production. The method published in Nature Chemistry could help to prevent severe side effects caused by drugs that can exist as enantiomers.
