Sector News

AstraZeneca spinout Entasis nabs Shire exec as CMO

November 4, 2019
Life sciences

After getting off a $75 million IPO last year, AstraZeneca’s antibiotics spinout Entasis has hired a former Shire executive to lead its R&D programs.

David Altarac, M.D., M.P.A., becomes its new chief medical officer next week and will replace Robin Isaacs, M.D., a four-year veteran of the company since its spinout, who is retiring. (Though he will be an adviser on the later-stage programs as they gear up for a regulatory review.)

In his new role, Altarac will be responsible for leading clinical development for Entasis’ lead programs, sulbactam-durlobactam and zoliflodacin, currently in phase 3, as well as the ETX0282CPDP program (which has had its issues), all the while boosting the biotech’s pipeline of pathogen-targeted antimicrobials.

He will in addition head up the teams for medical affairs, pharmacovigilance, quality and regulatory affairs.

He comes to the biotech from Shire, which has been bought out by Takeda (and seen a series of execs leave the now merged company), where he was senior vice president and head of global regulatory affairs, global drug safety and R&D quality and compliance. He’s also served a stint at NeoStem and more than 13 years at Merck.

Manos Perros, CEO at Entasis, said: “We are truly delighted to welcome David to the team. As our lead programs advance through late-stage development, David’s broad expertise and experience in biopharmaceutical R&D will help drive our strategy and prepare for commercialization, while ensuring quality and patient safety. We thank Robin for his years of dedication, insightfulness, and expertise that drove forward our pathogen-targeted antibacterial programs and look forward to continuing to work with him in his new capacity.”

Massachusetts-based Entasis spun out of AstraZeneca with an antibiotic drug discovery platform and funding in 2015. Since then, Entasis raised $82 million from backers including Clarus Lifesciences, Novo Holdings and Frazier Life Sciences, then got off its IPO last year, though at the lower end of the range.

Altarac added: “Entasis is spearheading a new model for antibiotic development and commercialization, making use of the latest technologies to deliver transformative treatments for patients with the highest unmet medical needs. I look forward to working closely with the team to translate ground-breaking science into meaningful new antimicrobials and to continue building our pipeline of innovative programs.”

By Ben Adams

Source: Fierce Biotech

Join the discussion!

Your email address will not be published. Required fields are marked *

Related News

January 17, 2021

SII expects WHO emergency approval of Covid-19 vaccine soon

Life sciences

The Serum Institute of India (SII) expects to soon receive World Health Organisation (WHO) emergency use authorisation for the Oxford University/AstraZeneca Covid-19 vaccine, produced for mid and low-income countries.

January 17, 2021

Sanofi to acquire clinical-stage biopharma firm Kymab for $1.45bn

Life sciences

According to the deal, Sanofi will gain full global rights to Kymab’s fully human monoclonal antibody, KY1005 that attaches to OX40-Ligand and can potentially treat various immune-mediated diseases and inflammatory ailments.

January 17, 2021

Moderna poaches Amgen vet as CCO, jump-starting commercial team as it rolls out COVID-19 vaccine

Life sciences

Moderna tapped veteran Amgen executive Corinne Le Goff to spearhead that effort as chief commercial officer.

Send this to a friend