AstraZeneca already has a Tagrisso approval for patients with previously untreated, EGFR-mutated lung cancer. But it’s shoring up its case with some clutch new data.
Friday, the British drugmaker said Tagrisso had beaten out Roche’s rival drug Tarceva and AstraZeneca’s own Iressa at helping patients live longer. The showing came as part of the phase 3 Flaura trial—the same study that helped net Tagrisso its approval last year based on a reduction in the risk of disease progression.
That overall survival win could be a crucial stat for oncologists deciding which drug to pick. And thanks to the initial round of Flaura data, Tagrisso is already steamrolling. In the first half of 2019, it reeled in $1.41 billion in global sales, a 92% jump over the year-ago period at constant exchange rates. U.S. sales also ramped up between Q1 and Q2, swelling by 16% to reflect “continued underlying demand growth,” AstraZeneca said in a financial filing.
That’s not to say it’s without competition, though. Just under a year ago, Pfizer snagged an FDA green light for once-failed Vizimpro in the first-line arena. While that drug is putting up tiny numbers, it’s still been a thorn in AstraZeneca’s side in the U.K., where cost watchdogs recently backed it for NHS use while shutting Tagrisso out.
Now, though, Tagrisso’s overall survival numbers—which will be unveiled in detail at a future medical meeting—could help bolster its position further. It’s considered by many to be the gold-standard endpoint in cancer trials, and Tagrisso’s the only drug that can claim that kind of win in this treatment setting.
AstraZeneca is certainly hoping so. It’s placed high hopes on the med with a $3 billion sales target that now looks to be within reach.
By: Carly Helfand
Source: Fierce Pharma
Big Pharma has long seen the potential for AI and machine learning to accelerate drug development. But Novo Nordisk is going a step further by channeling $200 million toward the creation of a computer that will outrun anything in existence.
Current methods for diagnosing Alzheimer’s disease rely on a complex combination of self- and caregiver-reported symptoms, a physical examination and either a PET scan or a spinal tap to look for evidence of amyloid plaque build-ups in the brain. But a new artificial intelligence-based method may make the diagnostic process a much more objective one.
There is lots of talk about diversity and inclusion in business, including in pharma and medtech. A new report by the Open Political Economy Network (OPEN), a think tank focusing on migration and diversity, released its “Minority Businesses Matter: Europe” report highlighting the successes and challenges of ethnic minority-owned businesses in Europe.